Amino Acid Sequence: Lys-Pro-Val
Molecular Formula: CisHaoN,04
Molecular Weight: 342.43 g/mol
PubChem CID: 125672
CAS Number: 67727-97-3
Synonyms: MSH (11-13), ACTH(11-13), alpha-MSH(11-13)
Total Amount of the Active Ingredient: 10mg (1 vial)
Shelf Life: 36 months
KPV is a tripeptide composed of lysine (K), proline (P), and valine (V), known for its anti-inflammatory and immunomodulatory properties. It is a naturally occurring fragment derived from the hormone alpha-melanocyte-stimulating hormone (α-MSH), which is involved in regulating inflammation and immune responses. KPV has gained attention in research for its ability to suppress pro-inflammatory cytokines and inhibit the activity of nuclear factor-kappa B (NF-κB), a key regulator of inflammation.
Due to its anti-inflammatory effects, KPV is being studied for its potential therapeutic applications in treating various inflammatory conditions, such as inflammatory bowel disease (IBD), dermatitis, and other autoimmune disorders. Its ability to reduce inflammation without suppressing the entire immune system makes it a promising candidate for treating chronic inflammatory diseases. Moreover, KPV has shown wound-healing properties and potential antimicrobial activity, further expanding its potential therapeutic uses. Research is ongoing to explore its clinical applications and optimize its delivery for medical treatments.
https://academic.oup.com/ibdjournal/article-abstract/14/3/324/4653598
https://pubmed.ncbi.nlm.nih.gov/18061177/
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